Y64: ICD10 Code for Contaminated medical or biological substances
Learn about Y64, the ICD10 code for Contaminated medical or biological substances. Understand symptoms, diagnosis, usage, and related codes.

Contaminated medical or biological substances (Y64) captures adverse events and errors occurring during surgical or medical care, such as breaches of sterile technique, incorrect dosages, contaminated substances, nonperformance of necessary care, or other unintentional misadventures. Prompt identification and documentation are critical for patient safety, quality improvement, and risk management.
Symptoms
- Postoperative infections due to sterile failure
- Complications from underdosing or overdosing medications
- Sepsis or systemic infection from contaminated products
- Unexpected deterioration due to untreated conditions
- Delayed healing, worsened conditions, or reoperations
- Signs of toxic exposure from biological contamination
- Emotional distress or trust issues following medical errors
Diagnosis
Diagnosis involves clinical evaluations, laboratory tests to detect infections or toxic exposures, medication reconciliation to confirm dosage errors, review of operative and nursing notes, and incident investigations by quality assurance teams. Root cause analyses are often conducted in healthcare settings following such events.
ICD10 Code Usage
The ICD10 code Y64 is used in hospital quality records, patient safety databases, insurance claims, malpractice investigations, and public health reports. Accurate coding helps in identifying systemic problems, improving clinical practices, ensuring patient compensation, and guiding regulatory and accreditation efforts.
Related Codes
- Y62 – Failure of sterile precautions during surgical and medical care
- Y63 – Failure in dosage during surgical and medical care
- Y65 – Other misadventures during surgical and medical care
- Y66 – Nonadministration of surgical and medical care
- Y69 – Unspecified misadventure during surgical and medical care
FAQs
Q1: What does ICD10 code Y64 classify?
A: It classifies adverse medical events such as sterile failures, dosage mistakes, contaminated substances, failure to provide necessary care, and other surgical or medical misadventures.
Q2: How are these incidents investigated?
A: Through internal hospital reviews, root cause analysis (RCA), peer reviews, and external audits where necessary.
Q3: Why is immediate reporting important?
A: Early detection minimizes patient harm, allows prompt corrective action, and improves healthcare outcomes.
Q4: Can these errors be prevented?
A: Yes, through proper training, adherence to protocols, safety checklists, and continuous quality improvement initiatives.
Q5: How does coding help healthcare quality improvement?
A: It identifies patterns of errors, informs safety initiatives, supports regulatory compliance, and promotes a culture of transparency and accountability.
Conclusion
Proper use of ICD10 code Y64 for Contaminated medical or biological substances ensures thorough tracking of healthcare-related misadventures, supports patient safety programs, improves clinical practices, and fosters accountability in medical and surgical care delivery.

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