E15 refers to Nondiabetic hypoglycemic coma, a group of conditions affecting the endocrine function of the pancreas outside of typical diabetes. These include severe hypoglycemia not related to diabetes and other rare pancreatic hormone imbalances such as insulinoma, glucagonoma, and other endocrine tumors.

Symptoms

Confusion or altered mental state – Common in hypoglycemic coma
Loss of consciousness – Severe cases of low blood sugar
Shakiness or sweating – Early signs of hypoglycemia
Seizures – If glucose drops too low for too long
Abdominal pain – Seen in some pancreatic endocrine disorders
Unexplained weight loss or flushing – Signs of insulinoma or glucagonoma
Nausea or fatigue – From hormone dysregulation

Diagnosis

Diagnosis of Nondiabetic hypoglycemic coma includes blood glucose testing, insulin and C-peptide levels, fasting glucose challenge, imaging (MRI or CT for tumors), and hormone-specific assays (e.g., glucagon, somatostatin). Close monitoring is essential to identify functional endocrine disorders of the pancreas.

ICD10 Code Usage

ICD10 code E15 is used by endocrinologists, emergency physicians, and internists to classify hypoglycemia-related comas and pancreatic endocrine disorders not related to diabetes. This ensures accurate treatment planning, endocrine evaluation, and billing classification.

Related Codes

E16 – Other disorders of pancreatic internal secretion

FAQs

Q1: What is ICD10 code E15?
A: This code documents Nondiabetic hypoglycemic coma, a condition of pancreatic hormone imbalance or nondiabetic hypoglycemia.

Q2: What causes these disorders?
A: Insulin overproduction (e.g., insulinoma), hormonal tumors, critical illness, fasting, or medications can trigger these conditions.

Q3: Are they life-threatening?
A: Nondiabetic hypoglycemic coma can be life-threatening without immediate treatment. Pancreatic endocrine disorders vary in severity.

Q4: How are they treated?
A: Acute glucose administration, surgical removal of hormone-secreting tumors, and medication to balance hormone levels.

Q5: Who manages these conditions?
A: Endocrinologists and sometimes surgical or critical care teams, depending on severity and cause.

Conclusion

ICD10 code E15 is vital for identifying and treating Nondiabetic hypoglycemic coma. It helps track endocrine dysfunctions beyond diabetes, enables emergency response to hypoglycemic coma, and ensures proper referral and follow-up for pancreatic hormone disorders.